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Product name
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(-)-Corey Lactone P-Phenylbenzoate alcohol ; BPCOD
|
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CAS No.
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31752-99-5
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Molecular Formula
|
C8H12O4
|
|
Grade Standard
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Medical grade
|
|
Appearance
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White to
off-white crystalline powder
|
|
COA of (-)-Corey Lactone P-Phenylbenzoate alcohol
|
|
ITEM
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SPECIFICATION
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RESULTS
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|
Appearance
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Off-white to
white crystalline powder
|
White
crystalline powder
|
|
Identification
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IR
spectrum of sample complies with the Reference Spectrum
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Complies
|
|
m.p.
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130.0 - 135.0℃
|
133.5-134.0℃
|
|
Purity (by
HPLC)
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> 99%
|
99.68%
|
|
Chiral Purity
(by HPLC)
|
> 99%
|
100.00%
|
·
Prostaglandin intermediate, is a building block for the
preparation of an analog of PGF2 [alpha], a potent and selective anti-glaucoma
drug.
·
As prostaglandins can cause strong contraction of the
uterus, it is applied to full-term pregnancy induced abortion, abortion and
contraception, and achieved some results. Prostaglandin treatment of asthma,
gastrointestinal ulcer disease, shock, hypertension and cardiovascular disease
may have a certain effect, which aroused people's attention.
·
The main physiological function of PG PGE2 can induce
inflammation, promote local vasodilatation, increased capillary permeability,
causing red, swollen, pain, fever and other symptoms. PGE2, PGA2 make arterial
smooth muscle relaxation, lower blood pressure. PGE2 and PGI2 inhibit gastric
acid secretion, promote gastrointestinal smooth muscle motility. Follicles
produce PGE2 and PGF2α play an important role in ovulation. PGF2α can ovarian
smooth muscle contraction, causing ovulation. Uterine release of PGF2α luteal
lysis. PGF2α released from the endometrium during childbirth can cause
contractions of the uterus to be strengthened and promote childbirth.
