1-CHLORO-2-DIMETHYLAMINOPROPANE CAS NO.:53309-35-6 is intermediate of Dioxopromethazine and Propizepine.
Condensation of 2-chloronicotinic acid with o-phenylenediamine leads directly to the tricyclic lactam Although the reaction involves amide formation and nucleophilic aromatic displacement of chlorine, the order of these steps is not known. Alkylation of the anion obtained by treatment if with the 1-chloro-2-dimethylaminopropane affords the antidepressant compound propizepine.
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