Acyl CoA synthetase (ACS) CAS 595495-92-4

Acyl CoA synthetase (ACS, EC 6.2.1.3) catalyzes the formation of acyl CoA from free fatty acids and coenzyme A. ACS of our company is a recombinant product, free of animal origin virus, with high purity and good activity.

Biochemical study: the content of free fatty acids (NEFA) in serum is very small, and most of them are bound to albumin. NEFA is directly related to oxidative stress, which can lead to diabetes by damaging islet cells and reducing the sensitivity of peripheral tissues to insulin. The concentration of free fatty acids will increase due to diabetes, severe liver disorders, hyperthyroidism and other diseases, such as insulin resistance / type 2 diabetes, obesity, metabolic syndrome, and will cause cardiovascular disease.

Enzymatic detection of free fatty acids has the advantages of fast, simple, high sensitivity, easy automation and large-scale detection. ACS is the first enzyme to start the free fatty acid enzyme detection kit, so it has a very important role and significance.

[Product Description]

Dosage form: white freeze-dried powder

Save buffer: Tris buffer, pH8.0

Enzyme activity: 60 U/mg protein

Activity unit: under the condition of pH 7.5 and 37 ° C, the amount of enzyme required to catalyze the reaction of free fatty acid and coenzyme A to generate 1 umol of acyl coenzyme A is defined as 1 U unit.

General information:

Source: gene recombinant expression

Molecular weight: about 70 KDa (detected by SDS-PAGE)

Purity: ≥ 90% (SDS-PAGE detection)

Storage conditions: freeze dried powder at 4 ℃ or long-term storage at - 20 ℃

Transportation conditions: ice bag with low temperature

Safety tips: not for human experiment