|
Product name
|
Amikacin intermediate 262368-30-9
Acidol-4Benzyloxycarbonyl-Amino-2Hydroxy Butyric
(CBZ-L-HABA)
|
|
Molecular Formula
|
C12H15NO5
|
|
Molecular Weight
|
253.25
|
|
CAS No.
|
40371-50-4
|
|
Quality Standard
|
99% up by HPLC,
medical grade
|
|
Appearance
|
White powder
|
|
COA of Amikacin Intermediate 40371-50-4
|
|
ITEMS
|
SPECIFICATION
|
RESULTS
|
|
DESCRIPTION
|
WHITE OR OFF-WHITE SOLID POWDER
|
OFF-WHITE SOLID POWDER
|
|
MELTING RANGE
|
75.0℃-79.0℃
|
76.0℃-78.5℃
|
|
LOSS ON DRYING
|
≤1.0%
|
0.12%
|
|
SPECIFIC ROTATION
|
-3.5°to -7.0°
|
-4.75°
|
|
ASSAY
|
≥98%
|
99.15%
|
|
RESIDUE ON IGNITION
|
≤1.0%
|
0.05%
|
|
CONCLUSION
|
CONFORMS TO THE ENTERPRISE STANDARD
|
|
STORAGE
|
AIRTIGHT, PROTECTED FROM LIGHT, IN COOL AND DRY PLACE.
|
Amikacin intermediate 262368-30-9(Acidol-4Benzyloxycarbonyl-Amino-2Hydroxy
Butyric (CBZ-L-HABA)) is a key
intermediate of Amikacin. Amikacin is an aminoglycoside
antibiotic, a white or off-white powder or a crystalline powder; almost
odorless and tasteless. Its mechanism of action is to act on ribosomes in
bacteria, inhibit bacterial protein synthesis, and destroy the integrity of
bacterial cell walls, causing bacterial cell membrane destruction and cell
death. Suitable for infections caused by Gram-negative bacilli and
penicillin-resistant Staphylococcus aureus.
