Product name: Bimatoprost
Synonyms:-
INCI name: Bimatoprost
CAS No.: 155206-00-1
EINECS: 642-890-9
Quality: assay 99.5%-102.0% up by HPLC
Molecular formula: C25H37NO4
Molecular weight: 415.57
Description:
Individuals may even use eyelash transplantations to improve the appearance of their eyelashes. The unique properties of eyelashes (e.g., relatively long telogen and short anagen phases compared with scalp hairs, slow rate of growth, and a lack of influence by androgens) may allow for specific aesthetic interventions to improve the appearance of natural eyelashes. Some over-the-counter (OTC) products may contain prostaglandin analogs that can affect eyelash growth, but neither the safety nor efficacy of these OTC cosmetics has been fully studied. Originally indicated for the reduction of intraocular pressure, the synthetic prostaglandin analog bimatoprost was recently approved for the treatment of hypotrichosis of the eyelashes. In a double-blinded, randomized, vehicle-controlled trial, bimatoprost safely and effectively grew natural eyelashes, making them longer, thicker, and darker. Bimatoprost was generally safe and well tolerated and appears to provide an additional option for individuals looking to improve the appearance of their eyelashes.
Specification (assay 99.5%-102.0% up by HPLC):
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Item
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Specification
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Description
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White powder
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Identification (by HPLC)
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RT of the sample should match with standard in the related substances
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Solubility
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Very soluble in ethanol, methanol, sparingly to slightly soluble in water
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Water
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≤1.0%
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Specific rotation [α]20D
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+33°~ +39°
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Residue on ignition
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≤0.1%
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Heavy metals
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≤10ppm
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Residue solvent
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Ethanol ≤0.5%
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Ethyl acetate ≤0.5%
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N-Hexane ≤0.029%
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Ether ≤0.5%
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15 β-bimatoprost
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≤0.2%
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15-keto derivative
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≤0.2%
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5,6-trans isomer
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≤0.2%
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Other single max impurity
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≤0.1%
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Total other impurities
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≤0.5%
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Purity
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≥99.0%
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Assay(by HPLC)
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99.5%~102%
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Production capacity: 100g/month
Storage condition: with ice bag for transportation, 2-8℃ for long term storage
Package material: vial, bottle
Package size:1g/vial, 5/vial, 10g/vial, 50g/bottle, 500g/bottle
