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CAS NO.:28981-97-7 Alprazolam;Xanax C17H13ClN4 Recreational Club Designer Anxiolytics；Depressant;Calming;Anticonvulsants Drug

Alprazolam, available under the trade name Xanax, is a potent, short-acting benzodiazepine anxiolytic—a minor tranquilizer.

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Alprazolam, available under the trade name Xanax, is a potent, short-acting benzodiazepine anxiolytic—a minor tranquilizer. It is commonly used for the treatment of anxiety disorders, especially of panic disorder, but also in the treatment of generalized anxiety disorder (GAD) or social anxiety disorder. In 2010 it was the 12th most prescribed medicine in the United States. Alprazolam, like other benzodiazepines, binds to specific sites on the GABAA receptor. It possesses anxiolytic, sedative, hypnotic, skeletal muscle relaxant, anticonvulsant, amnestic, and antidepressant properties. Alprazolam is available for oral administration as compressed tablets (CT), orally disintegrating tablet (ODT) and extended-release tablets (XR).
Greatest alleviation of generalized anxiety disorder (GAD) may take up to a week. It has been suggested that there is tolerance to the anxiolytic and antipanic effects of the drug, but not all authorities agree; tolerance will, however, develop to the sedative and hypnotic effects within a couple of days. Withdrawal symptoms or rebound symptoms may occur after ceasing treatment abruptly following a few weeks or longer of steady dosing, and may necessitate a gradual dose reduction. Other risks include increased rates of suicide, possibly due to disinhibition.
Alprazolam was first released by Upjohn (now a part of Pfizer) in 1981. The first approved use was of panic disorder, and within two years of its original marketing, Xanax became a blockbuster drug in the US. As of 2010, alprazolam is the most prescribed and the most misused benzodiazepine in the US. The potential for misuse among those taking it for medical reasons is controversial, with some expert reviews stating that the risk is low and similar to that of other benzodiazepine drugs. Others state that there is a substantial risk of misuse and dependence in both patients and non-medical users and that the high affinity binding, high potency, short elimination half-life, and rapid onset of action may increase the misuse potential of alprazolam. Compared to the large number of prescriptions, relatively few individuals increase their dose on their own initiative or engage in drug-seeking behavior. Alprazolam is classified as a Schedule IV controlled substance by the U.S. Drug Enforcement Administration (DEA).

Medical uses:

Alprazolam is mostly used to treat anxiety disorders, panic disorders, and nausea due to chemotherapy. Alprazolam may also be indicated for the treatment of generalized anxiety disorder, as well as for the treatment of anxiety conditions with co-morbid depression. The FDA label advises that the physician should periodically reassess the usefulness of the drug.

Panic disorder:

Alprazolam is effective in the relief of moderate to severe anxiety and panic attacks. However, it is not a first line treatment since the development of selective serotonin reuptake inhibitors. Alprazolam is no longer recommended in Australia for the treatment of panic disorder due to concerns regarding tolerance, dependence, and abuse. Most evidence shows that the benefits of alprazolam in treating panic disorder last only 4 to 10 weeks. However, people with panic disorder have been treated on an open basis for up to 8 months without apparent loss of benefit.
In the United States, alprazolam is FDA-approved for the treatment of panic disorder with or without agoraphobia. Alprazolam is recommended by the World Federation of Societies of Biological Psychiatry (WFSBP) for treatment-resistant cases of panic disorder where there is no history of tolerance or dependence.

Anxiety disorders:

Anxiety associated with depression is responsive to alprazolam. Clinical studies have shown that the effectiveness is limited to 4 months for anxiety disorders. However, the research into antidepressant properties of alprazolam is poor and has only assessed its short-term effects against depression. In one study, some long term, high-dosage users of alprazolam developed reversible depression. In the US, alprazolam is FDA-approved for the management of anxiety disorders (a condition corresponding most closely to the APA Diagnostic and Statistical Manual DSM-IV-TR diagnosis of generalized anxiety disorder) or the short-term relief of symptoms of anxiety. In the UK, alprazolam is recommended for the short-term treatment (2–4 weeks) of severe acute anxiety.
Nausea due to chemotherapy:

Alprazolam may be used in combination with other medications for chemotherapy-induced nausea and vomiting.
Adverse effects:

Xanax (alprazolam) 2 mg tri-score tablets

Possible side effects include:

Anterograde amnesia and concentration problems
Ataxia, slurred speech
Disinhibition
Drowsiness, dizziness, lightheadedness, fatigue, unsteadiness, and impaired coordination, vertigo
Dry mouth (infrequent)
Hallucinations (rare)
Jaundice (very rare)
Skin rash, respiratory depression, constipation
Suicidal ideation or suicide
Urinary retention (infrequent)

Overdose:

Main article: Benzodiazepine overdose
Overdoses of alprazolam can be mild to severe depending on the quantity ingested and if other drugs are taken in combination.
Alprazolam overdoses cause excess central nervous system (CNS) depression and may include one or more of the following symptoms:
Coma and death if alprazolam is combined with other substances.
Fainting
Hypotension (low blood pressure)
Hypoventilation (shallow breathing)
Impaired motor functions
Dizziness
Impaired balance
Impaired or absent reflexes
Muscle weakness
Orthostatic hypotension (fainting while standing up too quickly)
Somnolence (drowsiness)

Forms of alprazolam:

Alprazolam regular release and orally disintegrating tablets are available as 0.25 mg, 0.5 mg, 1 mg, and 2 mg tablets, while extended release tablets are available as 0.5 mg, 1 mg, 2 mg, and 3 mg. Alprazolam oral solutions are available as 0.5 mg/5 mL and as 1 mg/1 mL oral solutions. Inactive ingredients in alprazolam tablets and solutions include microcrystalline cellulose, corn starch, docusate sodium, povidone, sodium starch glycollate, lactose monohydrate, magnesium stearate, colloidal silicon dioxide, and sodium benzoate. In addition, the 0.25 mg tablet contains D&C Yellow No. 10 and the 0.5 mg tablet contains FD&C Yellow No. 6 and D&C Yellow No. 10.

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Shipping：

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Payment：

Bitcoin;WU;MG;Bank

Purity：

Pure

Appearance:

Conform

Date of delivery:

Within 48 hours when you finished the payment

Sales territory:

All over the world

Stock:

Enough

Transportation insurance:

Yes

Shipping origin:

HongKong

Synthesis of cycle:

2-7 days

Application range：

Recreational Club Drugs;Chemistry Experiment；psychedelic ；Reagent and Other

Manufacturer:

Universal drugs Lab

Expiration date：

5 Years



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