Detail:
5-(2-Aminopropyl)indole (5-API, 5-IT, PAL-571) is an indole and phenethylamine derivative with empathogenic effects. Its preparation was first reported by Albert Hofmann in 1962. It is a designer drug that has been openly sold as a recreational drug by online vendors since 2011.
Chemistry:
Although 5-IT is a positional isomer of the tryptamine drug αMT, the compound is not itself a tryptamine as the indole ring is substituted at the 5 position rather than at the 3 position. The compound is closer chemically to phenethylamine derivatives such as 5-APB. This is reflected in the compound's effects when used as a drug, which are reportedly stimulating rather than psychedelic.
Pharmacology:
5-IT acts as a triple monoamine releasing agent with EC50 values of 12.9 nM for dopamine, 13.3 nM for norepinephrine and 104.8 nM for serotonin and also as MAO-A inhibitor.
Dosage and effects:
Alexander Shulgin wrote briefly about 5-IT in TiHKAL saying: "at 20 milligrams orally, [it] is a long-lived stimulant producing increased heart-rate, anorexia, diuresis, and slight hyperthermia for about twelve hours." As 5-IT is not a tryptamine and thus not within the scope of the book, it is not discussed in any more detail than this.
The following symptoms can indicate 5-IT has been ingested: hyperthermia, tachycardia, increased blood pressure, dilated pupils (mydriasis), agitation, excessive sweating, jaw clenching, insomnia, disorientation, restlessness, anxiety, and tremor. It is an MAOI, and when combined with a contraindicated substance, it can lead to death.
Packing:
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Packing 1-4
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Shipping:
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Shipping 1-4
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Payment:
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Bitcoin;WU;MG;Bank
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Purity:
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Pure
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Appearance:
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Conform
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Date of delivery:
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Within 48 hours when you finished the payment
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Sales territory:
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All over the world
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Stock:
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Enough
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Transportation insurance:
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Yes
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Shipping origin:
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HongKong
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Synthesis of cycle:
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2-7 days
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Application range:
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Recreational Club Drugs;Chemistry Experiment;Reagent and Other
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Manufacturer:
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Universal drugs Lab
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Expiration date:
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5 Years
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