Detail:
1P-LSD or 1-propionyl-lysergic acid diethylamide is a psychedelic drug of the lysergamide class that is a derivative and functional analog of LSD and a homolog of ALD-52. It has been sold online as a designer drug since 2015.
Pharmacology:
While 1P-LSD shows only 38% the potency of LSD in mice, LSD is detected via LC-MS when 1P-LSD is incubated in human serum. This implies that 1P-LSD acts as a prodrug for LSD. This partially explains the effects of 1P-LSD, because the compound itself is unable to bind to the 5-HT2A receptors responsible for the effects of psychedelic drugs.
Prior to the publishing of the above cited research, pharmacologist David E. Nichols reportedly commented with his thoughts on 1P-LSD serotonin receptor binding:
“ I am sure that the 1-propionyl would also hydrolyze off of an indole, but I don't know whether in vivo conditions would work. In a chemistry lab, you can get off an N-benzoyl, so an N-propionyl will probably come off too. But in the body? I don't know the answer to that. The compound would not be active as the N-propionyl however. The way that LSD docks into the 5-HT2A receptor, the indole NH hydrogen bonds to serine 5.46. With the propionyl, it won't fit into the receptor. ”
Effects:
The effects profile of 1P-LSD is not well defined. It is generally thought to be comparable to that of LSD.
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Packing：
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Packing 1-4
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Shipping：
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Shipping 1-4
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Bitcoin;WU;MG;Bank
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Pure
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Conform
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Within 48 hours when you finished the payment
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Sales territory:
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All over the world
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Enough
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Yes
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HongKong
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Synthesis of cycle:
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2-7 days
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Application range：
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Recreational Club Drugs;Chemistry Experiment；psychedelic ；Reagent and Other
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Manufacturer:
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Universal drugs Lab
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Expiration date：
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5 Years
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