EtEraser™ SE Endotoxin Removal Kit
1. Product information
Lipopolysaccharide (LPS) is a bacterial endotoxin and a major
constituent of the cell walls of gramnegative bacteria. Recombinant protein
from E.coli usually contains high level of endotoxins. The removal of these
endotoxins is highly necessary for downstream processes.
EtEraser SE Endotoxin Removal kit are designed
to remove endotoxin contamination from aqueous solutions. The kits contain
endotoxin removal resin binds to reduce endotoxin levels in protein samples by
≥99% in less than 2 hours.
The kit includes a pre-packed endotoxin removal column
1.5 ml, Equilibration Buffer, Regeneration Buffer and pyrogen-free
collection tube and tips. The column has a high binding capacity of > 2,
000, 000 EU / ml. This product may be reused up to five times if properly
regenerated. The affinity resin is available in slurry and could be up-scaling
in biopharmaceutical process.
EtEraser SE Endotoxin Removal kit utilizes food grade modified ε-poly-L-lysine as
high affinity ligand for endotoxins. The resin is agarose beads which is very
stable and has no cytotoxic effect to human body. After purification, there
will no toxic residual remained in the samples. This endotoxin removal kit can
be used in protein drugs, vaccines, antibodies, DNA/RNA, polysaccharide and
other biological samples.
2. Product features
• high stability --- does not affect the activity of most of the
biological sample
• high bonding capacity --- >2000000 EU/ml
• non-toxic -----> Non-toxic food grade ligands, no cytotoxic
effects poly lysine
• high protein recovery --- >95% protein recovery for protein
samples
• high removal efficiency --- remove >99% endotoxin,
endotoxin level in the sample can be less than 0.1 EU/ml after endotoxin
removing process
• wide application range --- can be used in endotoxin removal
for proteins, peptides, antibodies, vaccines, polysaccharide and other
biological samples
