Production
Vitamin B12, CAS No. : 68-19-9, Item No. : 185758.
Vitamin B12, also known as cobalamin, is the only vitamin that contains metal elements.
Vitamin B12 physiological function is involved in the production of bone marrow red blood cells, prevent pernicious anemia;
To prevent nerve damage to the brain.
Used in a variety of classic and serum-free medium formulations.
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Functions
1. To improve the utilization of folic acid, it and folic acid are together with the synthesis of methionine (from high cysteine synthetase) and choline, producing Vitamin B12 application based pioneer substances such as methyl cobalamin and coenzyme B12 in purine and pyrimidine synthesis process, participating in the methylation process in many important compounds. When vitamin B12 deficiency, activities which transferred methyl groups from the methylenetetrahydrofolate reduced to make folic acid into no use of form, leading to folate deficiency.
2.Maintain the metabolism and function of the nerve myelin sheath. Lack of vitamin B12, can cause neurological disorders, degeneration of spinal cord, and can cause severe psychiatric symptoms. Vitamin B12 deficiency can cause peripheral neuritis. Children's lack of vitamin B12 early performance is emotional, dull, slow response, and finally leads to anemia.
3. Promote the development and maturation of red blood cells. The two acyl coenzyme A is converted to succinate coenzyme A, which is involved in the synthesis of three carboxylic acid cycle, in which the synthesis of A is related to the synthesis of heme.
4. Vitamin B12 is also involved in synthesis of deoxy nucleic acid (DNA), metabolism of fat, carbohydrate and protein, increasing the synthesis of nucleic acids and proteins.
An overview of vitamin B12, traits, physiological function, application are compiled by Eastern of Chemicalbook . (2016-12-10)
