TA-1 is a potent inhibitor of CK1 (Casein Kinase 1) and p38 MAPK (p38 Mitogen-Activated Protein Kinase). It has IC50 values of 6.4 nM for CK1ε, 6.8 nM for CK1δ, and 6.7 nM for p38 MAPK.
TA-1 is used in studies related to signal transduction pathways, particularly those involving CK1 and p38 MAPK. It has been used to study the differentiation of pluripotent stem cells into cardiomyocytes. TA-1 is involved in research related to autophagy and metabolic pathways.
Brand: Soarwin
CAS No.: 1784751-18-3
Molecular Formula: C20H12F3N3
Boiling point: 511.1±50.0 °C(Predicted)
Density: 1.337±0.06 g/cm3(Predicted)
Storage temp.: Store at -20°C
Solubility: DMF: 5 mg/ml; DMF:PBS(pH 7.2)(1:6): 0.14 mg/ml; DMSO: 3 mg/ml
