Buy Online Vardenafil CAS: 224785-90-4 from ANDSON BIOLOGICAL TECH. CO.,LTD
Name:Vardenafil
CAS ：224785-90-4
Formula：C23H32N6O4S
Molar mass：488.604g/mol g·mol−1
Assay : ≥98.0% (HPLC)
Form : powder
Color : white to beige
Vardenafil (Levitra) is an oral therapy for the treatment of erectile dysfunction. It is a selective inhibitor of cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5). Penile erection is a hemodynamic process initiated by the relaxation of smooth muscle in the corpus cavernosum and its associated arterioles. During sexual stimulation, nitric oxide is released from nerve endings and endothelial cells in the corpus cavernosum. Nitric oxide activates the enzyme guanylate cyclase resulting in increased synthesis of cyclic guanosine monophosphate (cGMP) in the smooth muscle cells of the corpus cavernosum. The cGMP in turn triggers smooth muscle relaxation, allowing increased blood flow into the penis, resulting in erection. The tissue concentration of cGMP is regulated by both the rates of synthesis and degradation via phosphodiesterases (PDEs). The most abundant PDE in the human corpus cavernosum is the cGMPspecific phosphodiesterase type 5 (PDE5); therefore, the inhibition of PDE5 enhances erectile function by increasing the amount of cGMP.
How does it work?
[vardenafil, or levitra, treats erectile dysfunction]
Vardenafil can help a man get and maintain an erection.
During a penile erection, the penis fills with blood.
The blood vessels that supply the penis with blood expand, or dilate, and the vessels that take blood away from the penis contract. The two large chambers in the penis, known as the corpus cavernosa, fill with blood.
As the blood accumulates in the penis, an erection results.
Vardenafil belongs to a class of drugs called phosphodiesterase type-5 (PDE5) inhibitors. A PDE5 inhibitor stops PDE5 from constricting the arteries.
By relaxing the arteries, vardenafil enhances blood flow when a man is sexually aroused.
The active ingredient works on the chain of reactions within the penis during arousal.
When a male is sexually aroused, nitric oxide is released into his penis, and this triggers a chain of reactions.
What are the side effects of vardenafil?
The most common side effects of vardenafil are facial flushing (reddening), headaches, stomach upset, diarrhea, flu like symptoms, and nausea. Vardenafil also may cause chest pain, low blood pressure, blurred vision and changes in color vision, abnormal ejaculation and priapism (painful erection lasting more than 6 hours). Patients should seek immediate medical help if they experience an erection lasting more than 4 hours. Rare cases of sudden loss of hearing have been reported with phosphodiesterase inhibitors such as vardenafil, sometimes associated with ringing in the ears and dizziness. If changes in hearing occur, patients should discontinue their vardenafil and seek immediate medical attention.
